Phenotypes associated with this allele

• Allele Symbol: Crocc^tm1Tili
• Allele Name: targeted mutation 1, Tiansen Li
• Allele ID: MGI:3580447
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crocc^tm1Tili/Crocc^tm1Tili	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3581406

Genotype
MGI:3581406

hm1

• Allelic Composition: Crocc^tm1Tili/Crocc^tm1Tili
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

retina photoreceptor degeneration ( J:98885 )

• show no apparent functional deficits in phototransduction and ciliary beating in sensory cilia; however, photoreceptors degenerate by 18 months showing shortening, disorganization and loss of the outer segments, reduced thickens of the cell nuclear layer, and mislocalization of rod and cone opsins

immune system

lung inflammation ( J:98885 )

• an increased incidence of lymphocyte infiltration around bronchioles and blood vessels in18 to 24 months old mutant lungs

respiratory system

lung inflammation ( J:98885 )

• an increased incidence of lymphocyte infiltration around bronchioles and blood vessels in18 to 24 months old mutant lungs

nervous system

retina photoreceptor degeneration ( J:98885 )

• show no apparent functional deficits in phototransduction and ciliary beating in sensory cilia; however, photoreceptors degenerate by 18 months showing shortening, disorganization and loss of the outer segments, reduced thickens of the cell nuclear layer, and mislocalization of rod and cone opsins