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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Abca1tm1.1Jp
targeted mutation 1.1, John S Parks
MGI:3577725
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Abca1tm1.1Jp/Abca1tm1.1Jp involves: 129S6/SvEvTac * C57BL/6 MGI:3578115


Genotype
MGI:3578115
hm1
Allelic
Composition		 Abca1tm1.1Jp/Abca1tm1.1Jp
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca1tm1.1Jp mutation (0 available); any Abca1 mutation (88 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:98093 )
• decreased levels of total plasma cholesterol, free cholesterol, and esterified cholesterol
abnormal circulating phospholipid level ( J:98093 )
• decreased phospholipid level

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Tangier disease DOID:1388 OMIM:205400
 J:98093




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory