Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh11tm1Peri mutation
(0 available);
any
Myh11 mutation
(93 available)
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muscle
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• bladder smooth muscle exhibited reduced rate and extent of tension development/force generation in response to increasing KCl concentrations compared to wildtype
• mesenteric vessels under KCl depolarization contracted at a slower rate (decreased velocity of shortening) than in wildtype
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|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh11tm1Peri mutation
(0 available);
any
Myh11 mutation
(93 available)
|
|
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respiratory system
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• lower rate of bronchoconstriction during the initial 4 seconds in response to methacholine
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• the time to peak baseline airway resistance (RAW) was significantly longer than in widl-type in response to methacholine
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homeostasis/metabolism
Allelic
Composition |
Myh11tm1Peri/Myh11+
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Genetic
Background |
involves: 129 * C57BL/6 |
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh11tm1Peri mutation
(0 available);
any
Myh11 mutation
(93 available)
|
|
|
muscle
|
|
• bladder smooth muscle exhibited reduced rate and extent of tension development/force generation in response to increasing KCl concentrations compared to wildtype
|
Analysis Tools