About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tnfsf4Ath1-PERA/EiJ
PERA/EiJ
MGI:3576370
Summary 2 genotypes


Genotype
MGI:3576512
hm1
Allelic
Composition
Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic
Background
B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf4Ath1-PERA/EiJ mutation (1 available); any Tnfsf4 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• HDL cholesterol levels are higher in mice homozygous for the PERA/EiJ allele than in homozygotes for the C57BL/6J allele
• homozygotes for the PERA allele maintain high HDL cholesterol levels when fed a high-fat diet

cardiovascular system
• homozygous mice develop smaller aortic fatty streaks than do C57BL/6J control mice when fed a high-fat diet




Genotype
MGI:3576511
ht2
Allelic
Composition
Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-C57BL/6J
Genetic
Background
B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf4Ath1-C57BL/6J mutation (0 available); any Tnfsf4 mutation (22 available)
Tnfsf4Ath1-PERA/EiJ mutation (1 available); any Tnfsf4 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice heterozygous for the PERA/EiJ allele exhibit higher HDL cholesterol levels than do those homozygous for the C57BL/6J allele





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/09/2022
MGI 6.21
The Jackson Laboratory