Mouse Genome Informatics
hm1
    Park7tm1Dsp/Park7tm1Dsp
B6.129P2-Park7tm1Dsp
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
homeostasis/metabolism
• increased striatal denervation and dopaminergic neuron loss induced by 1-methyl-4pheny-1,2,3,6-terahydropyrindine
• mutant embryonic cortical neurons showed increased sensitivity to oxidative insults

behavior/neurological
• showed hypo-locomotion when subjected to amphetamine challenge