All Phenotypes Cacna1g<tm1Stl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cacna1g^tm1Stl
targeted mutation 1, Susumu Tonegawa
MGI:3530499

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Camk2a-cre)CW2Stl/0	involves: C57BL/6	MGI:3531191
cn2	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Kcnc2-cre)K128Stl/0	involves: C57BL/6	MGI:3531192

Allelic Composition	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Camk2a-cre)CW2Stl/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1g^tm1Stl mutation (1 available); any Cacna1g mutation (102 available)
Tg(Camk2a-cre)CW2Stl mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:96099 )

N	• no disruption of sleep patterns or reduction in total sleep are seen

Allelic Composition	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Kcnc2-cre)K128Stl/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacna1g^tm1Stl mutation (1 available); any Cacna1g mutation (102 available)
Tg(Kcnc2-cre)K128Stl mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal sleep pattern ( J:96099 )

• during the light period mutants display fragmented sleep with frequent brief wakenings, more total wake bouts, and non-REM bouts are much shorter

• increased delta wave power is seen during non-REM sleep

fragmentation of sleep/wake states ( J:96099 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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