behavior/neurological
|
|
• mice exhibit normal rearing, social preference, acoustic startle, and prepulse inhibition
(J:169472)
|
|
|
• following contextual fear conditioning, mice exhibit reduced freezing compared with wild-type mice
(J:169472)
• however, cued fear conditioning is normal
(J:169472)
|
|
|
• mice spend less time attending a novel object in a short-term novel object recognition test compared with wild-type mice
(J:169472)
|
|
|
• mice exhibit longer latency to finding a visible platform in a Morris water maze likely due to decreased swim speed compared with wild-type mice
(J:169472)
|
|
|
• mice exhibit longer latency to finding a visible platform in a Morris water maze likely due to decreased swim speed compared with wild-type mice
(J:169472)
|
|
|
• mice exhibit an increase in activity along the periphery of a novel environment compared with wild-type mice
(J:169472)
|
hypoactivity
(
J:169472
)
|
|
• during the first 5 minutes in a novel environment
(J:169472)
|
homeostasis/metabolism
|
|
• in the brain, muscle, heart, testes, and serum
(J:169472)
• however, kidney levels are normal
(J:169472)
|
|
|
(J:169472)
|
|
|
• in the prefrontal cortex, hippocampus, and neostriatum
(J:169472)
|
growth/size
|
|
(J:169472)
|
Mouse Models of Human Disease |
OMIM ID | Ref(s) | |
| Creatine Deficiency Syndrome, X-Linked | 300352 | J:169472 | |
