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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kcnn2tm1.1Jpad
targeted mutation 1.1, John P Adelman
MGI:3522425
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Kcnn2tm1.1Jpad/Kcnn2tm1.1Jpad Not Specified MGI:3527278


Genotype
MGI:3527278
hm1
Allelic
Composition
Kcnn2tm1.1Jpad/Kcnn2tm1.1Jpad
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn2tm1.1Jpad mutation (1 available); any Kcnn2 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• prior to and after apamin treated dopamine neurons exhibit a higher mean inter-spike interval compared with wild-type neurons
• the apamin sensitive component of the medium afterhyperpolarization current is absent from CA1 neurons, however hippocampal morphology and slow afterhyperpolarization currents are normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory