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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccr5tm1Sush
targeted mutation 1, Kouji Matsushima
MGI:3522335
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ccr5tm1Sush/Ccr5tm1Sush B6.129P2-Ccr5tm1Sush MGI:3527433


Genotype
MGI:3527433
hm1
Allelic
Composition
Ccr5tm1Sush/Ccr5tm1Sush
Genetic
Background
B6.129P2-Ccr5tm1Sush
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr5tm1Sush mutation (0 available); any Ccr5 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• attenuated chemotactic activity of blood mononuclear cells toward the Ccr5 specific chemokine Ccl4 but not Cxcr3
• splenic CD8+ T cell proliferative response to wild-type peyer's patch CD11c+ dendritic cells was decreased compared to controls

hematopoietic system
• attenuated chemotactic activity of blood mononuclear cells toward the Ccr5 specific chemokine Ccl4 but not Cxcr3
• splenic CD8+ T cell proliferative response to wild-type peyer's patch CD11c+ dendritic cells was decreased compared to controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory