Mouse Genome Informatics
hm1
    Ccr5tm1Sush/Ccr5tm1Sush
B6.129P2-Ccr5tm1Sush
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
immune system
• attenuated chemotactic activity of blood mononuclear cells toward the Ccr5 specific chemokine Ccl4 but not Cxcr3
• splenic CD8+ T cell proliferative response to wild-type peyer's patch CD11c+ dendritic cells was decreased compared to controls

hematopoietic system
• attenuated chemotactic activity of blood mononuclear cells toward the Ccr5 specific chemokine Ccl4 but not Cxcr3
• splenic CD8+ T cell proliferative response to wild-type peyer's patch CD11c+ dendritic cells was decreased compared to controls