mortality/aging
cardiovascular system
|
• a single great artery gives rise to the coronary arteries, aorta and pulmonary arteries, with a short main pulmonary artery segment
|
|
• primum atrial septal defect
|
|
• a common atrioventricular canal is present
|
|
• outflow tract regurgitation is seen
|
craniofacial
|
• enlarged frontal bone resulting in a dome-shaped head
|
short maxilla
(
J:94456
)
micrognathia
(
J:94456
)
|
• short nasal bones
|
domed cranium
(
J:94456
)
hearing/vestibular/ear
immune system
limbs/digits/tail
short limbs
(
J:94456
)
skeleton
|
• enlarged frontal bone resulting in a dome-shaped head
|
short maxilla
(
J:94456
)
micrognathia
(
J:94456
)
|
• short nasal bones
|
domed cranium
(
J:94456
)
hematopoietic system
Mouse Models of Human Disease |
OMIM ID | Ref(s) | |
| Atrial Septal Defect 1; ASD1 | 108800 | J:94456 | |
| Atrioventricular Septal Defect; AVSD | 606215 | J:94456 | |
| DiGeorge Syndrome; DGS | 188400 | J:94456 | |