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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Gfap-cre)73.12Mvs
transgene insertion 73.12, Michael V Sofroniew
MGI:3522215
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rai1tm2.1Luo/Rai1tm2.1Luo
Tg(Gfap-cre)73.12Mvs/? 		either: (involves: 129S1/Sv * BALB/c * C57BL/6 * C57BL/6NHsd) or (involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NHsd) MGI:5817666
cn2
 		Smotm2Amc/Smotm2Amc
Tg(Gfap-cre)73.12Mvs/0 		involves: 129X1/SvJ * BALB/c * C57BL/6NHsd MGI:4838615


Genotype
MGI:5817666
cn1
Allelic
Composition		 Rai1tm2.1Luo/Rai1tm2.1Luo
Tg(Gfap-cre)73.12Mvs/?
Genetic
Background		 either: (involves: 129S1/Sv * BALB/c * C57BL/6 * C57BL/6NHsd) or (involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NHsd)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Tg(Gfap-cre)73.12Mvs mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:237687 )
• mice do not exhibit differences in behavior, motor function or body weight




Genotype
MGI:4838615
cn2
Allelic
Composition		 Smotm2Amc/Smotm2Amc
Tg(Gfap-cre)73.12Mvs/0
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6NHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smotm2Amc mutation (1 available); any Smo mutation (39 available)
Tg(Gfap-cre)73.12Mvs mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:165495 )
N
• mice exhibit normal forebrain morphology and cytoarchitecture
• the number of astrocytes in the cortex is normal
astrocytosis ( J:165495 )
• mild in the cortex




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory