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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(11Cops3-Gid4)2Jrl
deletion, Chr 11, James R Lupski 2
MGI:3521986
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Del(11Cops3-Gid4)2Jrl/+ involves: 129S7/SvEvBrd * C57BL/6 MGI:3522006


Genotype
MGI:3522006
ht1
Allelic
Composition
Del(11Cops3-Gid4)2Jrl/+
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice display defective context-dependent learning relative to wild-type mice
• in a novel area, mice are hypoactive, spend less time moving and travel shorter distances
• in an open field, mice rear more and spend more time exploring the center of an open field than wild-type mice
• in an open field, mice rear more than wild-type mice
• in a novel area, mice are hypoactive, spend less time moving and travel shorter distances

craniofacial
• length and height at tip were statistically shorter
• flat to slightly concave snout sometimes curved to the right or left
• variably shorter snout often close to normal length

vision/eye
• more widely spaced eyes but distance variable, often near normal

growth/size/body
• flat to slightly concave snout sometimes curved to the right or left
• variably shorter snout often close to normal length
• mice were significantly heavier than wild-type littermates at 10 weeks of age

skeleton
• length and height at tip were statistically shorter

Mouse Models of Human Disease
OMIM ID Ref(s)
Smith-Magenis Syndrome; SMS 182290 J:94405





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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory