Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spout1tm1Mxu mutation
(0 available);
any
Spout1 mutation
(12 available)
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mortality/aging
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• mice die between E2.5 and E3.5
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Allelic
Composition |
Spout1tm1Mxu/Spout1+
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Genetic
Background |
involves: 129 * C57BL/6 |
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spout1tm1Mxu mutation
(0 available);
any
Spout1 mutation
(12 available)
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cellular
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• reduced apoptosis and DNA fragmentation is seen in splenocytes, thymocytes, and MEFs after treatment with apoptotic stimuli
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• reduced amount of spontaneous apoptosis during spermatogenesis relative to wild-type
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reproductive system
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• reduced amount of spontaneous apoptosis during spermatogenesis relative to wild-type
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dffatm1Mxu mutation
(0 available);
any
Dffa mutation
(16 available)
Spout1tm1Mxu mutation
(0 available);
any
Spout1 mutation
(12 available)
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cellular
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• apoptosis and DNA fragmentation were essentially eliminated in splenocytes and thymocytes after treatment with apoptotic stimuli
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Analysis Tools
