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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Acvr1ctm1Cfi
targeted mutation 1, Carlos F Ibanez
MGI:3512292
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Acvr1ctm1Cfi/Acvr1ctm1Cfi involves: 129P2/OlaHsd * 129/Sv MGI:3512297
hm2
Acvr1ctm1Cfi/Acvr1ctm1Cfi involves: 129P2/OlaHsd * C57BL/6 MGI:3512300
cx3
Acvr1ctm1Cfi/Acvr1c+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
involves: 129 * C57BL/6 MGI:3625850
cx4
Acvr1ctm1Cfi/Acvr1ctm1Cfi
Nodaltm1Rob/Nodal+
involves: 129P2/OlaHsd * 129/Sv MGI:3512303
cx5
Acvr1btm1Enl/Acvr1b+
Acvr1ctm1Cfi/Acvr1ctm1Cfi
involves: 129P2/OlaHsd * 129/Sv MGI:3512304


Genotype
MGI:3512297
hm1
Allelic
Composition
Acvr1ctm1Cfi/Acvr1ctm1Cfi
Genetic
Background
involves: 129P2/OlaHsd * 129/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1ctm1Cfi mutation (1 available); any Acvr1c mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• no abnormalities were detected in growth, the morphology of the gut, skeleton, spleen, and cerebellum, glucose and insulin levels, or left-right patterning




Genotype
MGI:3512300
hm2
Allelic
Composition
Acvr1ctm1Cfi/Acvr1ctm1Cfi
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1ctm1Cfi mutation (1 available); any Acvr1c mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• no abnormalities were detected in growth or left-right patterning




Genotype
MGI:3625850
cx3
Allelic
Composition
Acvr1ctm1Cfi/Acvr1c+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1ctm1Cfi mutation (1 available); any Acvr1c mutation (39 available)
Gdf1tm1Sjl mutation (1 available); any Gdf1 mutation (8 available)
Nodaltm1Rob mutation (1 available); any Nodal mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3512303
cx4
Allelic
Composition
Acvr1ctm1Cfi/Acvr1ctm1Cfi
Nodaltm1Rob/Nodal+
Genetic
Background
involves: 129P2/OlaHsd * 129/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1ctm1Cfi mutation (1 available); any Acvr1c mutation (39 available)
Nodaltm1Rob mutation (1 available); any Nodal mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• expected numbers of compound mutants are detected at weaning




Genotype
MGI:3512304
cx5
Allelic
Composition
Acvr1btm1Enl/Acvr1b+
Acvr1ctm1Cfi/Acvr1ctm1Cfi
Genetic
Background
involves: 129P2/OlaHsd * 129/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1btm1Enl mutation (0 available); any Acvr1b mutation (36 available)
Acvr1ctm1Cfi mutation (1 available); any Acvr1c mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• expected numbers of compound mutants are detected at weaning





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory