mortality/aging
• Background Sensitivity: mice on a mixed C57BL/6N and FVB/N background survive up to 4 weeks compared with mice on a coisogenic C57BL/6N background that do not survive beyond E17.5
|
cardiovascular system
N |
• Background Sensitivity: mice on a mixed C57BL/6N and FVB/N background do not exhibit ventricular septal defects unlike mice on a coisogenic C57BL/6N background
|
• interstitial peritubular capillaries exhibit thicker endothelial wall and lack fenestrae, diaphragms and caveolae compared with wild-type mice
|
endocrine/exocrine glands
• larger interstitial spaces than in wild-type mice
|
• at 3 weeks
|
growth/size/body
• at P15
|
hematopoietic system
small spleen
(
J:203907
)
• at 3 weeks
|
renal/urinary system
small kidney
(
J:203907
)
• at 3 weeks
|
pale kidney
(
J:203907
)
homeostasis/metabolism
limbs/digits/tail
kinked tail
(
J:203907
)
• at P15
|
immune system
small spleen
(
J:203907
)
• at 3 weeks
|