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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Amy1TAg)354Knw
transgene insertion 354, Barbara Knowles
MGI:3056366
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Amy1TAg)354Knw/0 C57BL/6J-Tg(Amy1TAg)354Knw MGI:3835476


Genotype
MGI:3835476
tg1
Allelic
Composition
Tg(Amy1TAg)354Knw/0
Genetic
Background
C57BL/6J-Tg(Amy1TAg)354Knw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Amy1TAg)354Knw mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• foci of lipid-containing anaplastic cells are detected in numerous organs including liver, lung, spleen, heart, and adrenals
• in 2 of 12 mice with tumors
• 40% of mice develop hibernomas (brown adipose tissue tumors)

liver/biliary system
• in 2 of 12 mice with tumors





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory