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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
rda
roundabout
MGI:3055794
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
rda/rda C57BL/6J-rda/JKjn MGI:5437997
ht2
rda/rda+ C57BL/6J-rda/JKjn MGI:6154680


Genotype
MGI:5437997
hm1
Allelic
Composition
rda/rda
Genetic
Background
C57BL/6J-rda/JKjn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rda mutation (1 available); any rda mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Cochlear hair cell abnormalities in rda/rda and Elmod1rda-2J/Elmod1rda-2J mice

hearing/vestibular/ear
• in a few outer hair cells at P7 and P10
• in some cells at P15
• in a few outer hair cells at P7 and P10 adjacent to the kinocilium
• degeneration in all outer hair cells at P15
• profound by 5 weeks

behavior/neurological

nervous system
• in a few outer hair cells at P7 and P10
• in some cells at P15
• in a few outer hair cells at P7 and P10 adjacent to the kinocilium
• degeneration in all outer hair cells at P15




Genotype
MGI:6154680
ht2
Allelic
Composition
rda/rda+
Genetic
Background
C57BL/6J-rda/JKjn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
rda mutation (1 available); any rda mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
N
• heterozygotes have normal hearing





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory