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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tnfsf8tm1Pod
targeted mutation 1, Eckhard Podack
MGI:3054968
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tnfsf8tm1Pod/Tnfsf8tm1Pod B6.129X1-Tnfsf8tm1Pod MGI:3055175


Genotype
MGI:3055175
hm1
Allelic
Composition
Tnfsf8tm1Pod/Tnfsf8tm1Pod
Genetic
Background
B6.129X1-Tnfsf8tm1Pod
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf8tm1Pod mutation (1 available); any Tnfsf8 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increased host survival and decreased weight loss are seen after transplant of 1x106 fully allogeneic BALB/c CD4+ T cells into lethally irradiated homozygous mutant mice compared to wild-type mice
• no difference in survival is seen at higher CD4+ T cell concentration





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory