About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(MtTPRMET)243Lng
transgene insertion 243, T Jake Liang
MGI:3054048
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(MtTPRMET)243Lng/0 FVB/N-Tg(MtTPRMET)243Lng MGI:3800807


Genotype
MGI:3800807
tg1
Allelic
Composition
Tg(MtTPRMET)243Lng/0
Genetic
Background
FVB/N-Tg(MtTPRMET)243Lng
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MtTPRMET)243Lng mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• at 18 months of age, one female mouse exhibited an orbital giant cell ostersarcoma

neoplasm
• one female mouse developed mammary cancer at 6 months of age
• multiparous female mice exhibit hypoplastic alveolar nodules that contain foci of microscopic carcinomas
• all multiparous female mice develop scirrhous, papillary, or nodular mammary tumors
• at 6 to 9 months of age, female mice develop lymphoblastic lymphomas of the mammary gland and lymph nodes
• female mice develop spindle cell sarcomas
• at 18 months of age, one female mouse exhibited an orbital giant cell ostersarcoma

endocrine/exocrine glands
• multiparous females exhibit hypoplastic alveolar nodules
• one female mouse developed mammary cancer at 6 months of age
• multiparous female mice exhibit hypoplastic alveolar nodules that contain foci of microscopic carcinomas
• all multiparous female mice develop scirrhous, papillary, or nodular mammary tumors

integument
• multiparous females exhibit hypoplastic alveolar nodules
• one female mouse developed mammary cancer at 6 months of age
• multiparous female mice exhibit hypoplastic alveolar nodules that contain foci of microscopic carcinomas
• all multiparous female mice develop scirrhous, papillary, or nodular mammary tumors





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/12/2022
MGI 6.17
The Jackson Laboratory