Phenotypes associated with this allele

• Allele Symbol: ctl
• Allele Name: curly tail-like
• Allele ID: MGI:3045165
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	ctl/ctl	A/WySnJ-ctl/GrsrJ	MGI:3051505

Genotype
MGI:3051505

hm1

• Allelic Composition: ctl/ctl
• Genetic Background: A/WySnJ-ctl/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

ctl/ctl tail image

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:91389 )

N • hearing of 2 homozygous mutant mice was normal at 6 weeks of age as determined by acoustic brainstem response (ABR)

immune system

arthritis ( J:91389 )

• mild spinal arthritis was detected at 3 months by pathology screen

limbs/digits/tail

abnormal caudal vertebrae morphology ( J:91389 )

• tail vertebrae are abnormally shaped, causing the tail to curl or kink; skeleton appeared otherwise normal on X-ray images

curly tail ( J:91389 )

• incompletely penetrant: matings of ctl/ctl to ctl/+ mice yielded 26% affected progeny, indicating approximately 50% penetrance in this background

skeleton

arthritis ( J:91389 )

• mild spinal arthritis was detected at 3 months by pathology screen

abnormal caudal vertebrae morphology ( J:91389 )

• tail vertebrae are abnormally shaped, causing the tail to curl or kink; skeleton appeared otherwise normal on X-ray images

vision/eye

vision/eye phenotype ( J:91389 )

N • eyes of homozygous mutant mice examined ophthalmoscopically at 6 weeks and 3 months of age appeared normal

nervous system

hydrocephaly ( J:91389 )

• mild: detected at 3 months by pathology screen; not associated with cerebellar abnormality in liveborn mice