• no fetuses observed between E7.5 and E9.5

• hepatic iron concentrations did not differ from those of wild-type mice through 1 year of age, though treatment with iron dextran elicited a significantly higher increase in hepatic iron in mutant mice than in wild-type mice

• urinary porphyrin concentrations did not differ from those of wild-type mice prior to treatment with delta-aminolevulinic acid (ALA), though treatment with either ALA alone or with both ALA and iron elicited significantly higher increases in porphyrin concentrations than in mutant mice than in wild-type mice

• increased urinary porphyrin concentration (hepatic levels were also increased)