Mouse Genome Informatics
hm1
    Mpltm1Fjs/Mpltm1Fjs
involves: 129 * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
hematopoietic system
• levels of megakaryocyte progenitors reduced by about 50%
• fewer megakaryocytes generated in response to thrombopoietin and the ploidy of cells produced was lower
• less of an increase in platelets 5 days after thrombopoietin treatment

Mouse Models of Human Disease
OMIM IDRef(s)
Amegakaryocytic Thrombocytopenia, Congenital; CAMT 604498 J:87416