About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gabrr1tm1Llu
targeted mutation 1, Luo Lu
MGI:2683490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gabrr1tm1Llu/Gabrr1tm1Llu involves: 129S4/SvJae * C57BL/6 MGI:2683491


Genotype
MGI:2683491
hm1
Allelic
Composition
Gabrr1tm1Llu/Gabrr1tm1Llu
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrr1tm1Llu mutation (1 available); any Gabrr1 mutation (34 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• increase in mechanical pain sensitivity relative to wild-type, as shown by a decrease in the threshold for mechanical pain production in the von Frey filament test

nervous system
• altered GABA-mediated spinal cord response; the effect of GABA on depolarization potentials is less effective than in wild-type

taste/olfaction
• mutants are more sensitive to the smell of citral odorant than wild-type mice, moving out of the chamber containing the odorant significantly faster than controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory