Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrg2tm2Lusc mutation
(1 available);
any
Gabrg2 mutation
(41 available)
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrg2tm2Lusc mutation
(1 available);
any
Gabrg2 mutation
(41 available)
Tg(Camk2a-cre)2834Lusc mutation
(0 available)
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mortality/aging
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• a rapid decline in health is observed by the end of the fourth postnatal week and mice die within 3 days of overt signs of stress including reduced locomotion, round pupils, and reduced weight gain
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behavior/neurological
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• lack of locomotion is observed as health declines
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• some mice exhibit overt epilepsy within several days prior to death; typical seizures start with rearing adn loss of postural control, followed by running fits and violent convulsions
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nervous system
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• some mice exhibit overt epilepsy within several days prior to death; typical seizures start with rearing adn loss of postural control, followed by running fits and violent convulsions
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrg2tm2Lusc mutation
(1 available);
any
Gabrg2 mutation
(41 available)
Tg(Camk2a-cre)T50Stl mutation
(0 available)
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mortality/aging
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• mice die around 7 weeks of age
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