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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc22a2tm1Ahs
targeted mutation 1, Alfred H Schinkel
MGI:2680270
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc22a2tm1Ahs/Slc22a2tm1Ahs involves: 129P2/OlaHsd * FVB MGI:2680274


Genotype
MGI:2680274
hm1
Allelic
Composition
Slc22a2tm1Ahs/Slc22a2tm1Ahs
Genetic
Background
involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc22a2tm1Ahs mutation (1 available); any Slc22a2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• homozygotes are viable, fertile, and show normal plasma clinical chemistry as well as normal liver, kidney, and intestine histology
• at 20 min after i.v. administration of [14C]-tetraethylammonium (TEA) at 0.2 mg/kg, no significant differences are observed in the distribution and excretion of this prototypic organic cation relative to wild-type controls, except for the brain, where levels are reduced with borderline significance





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory