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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Noa
Naruto Otsuka atrichia
MGI:2667674
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Noa/Noa+ NOA MGI:2667689


Genotype
MGI:2667689
ht1
Allelic
Composition
Noa/Noa+
Genetic
Background
NOA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• often exhibit scratching behavior suggestive of chronic pruritus

hematopoietic system
• large number of mast cells are present around the lesions

immune system
• large number of mast cells are present around the lesions

integument
• no growth of pelage hair throughout life
• mice become completely hairless and smooth skinned in adulthood
• curly juvenile hair begins to appear thinly over the body starting at 5 days of age; lose juvenile hair progressively with age and become hairless by 12 weeks of age
• some hair follicle cysts filled with eosinophilic mass appear in the hypodermis within a few days after birth and increase in number and size until the 12th week of age
• thin vibrissae
• crooked vibrissae
• vibrissae are lost at around 12 weeks of age
• thickness of the dermis is increased due to proliferation of inflammatory cells and collagen bundles
• epidermis adjacent to lesions shows hyperkeratosis
• in regions of lesions
• in regions of lesions
• epidermis shows desquamation, with separation from the basal layer
• develop ulcerative skin lesions starting at 10 weeks of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Dermatitis, Atopic 603165 J:43274





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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory