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Allele Symbol Allele Name Allele ID |
Tg(PSEN1)1098Citr transgene insertion 1098, Martin Citron MGI:2664249 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• amyloid deposition is enhanced when the PSEN1 transgene is also expressed by mutants; deposition is noted by 30-45 days of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice do not exhibit neurodegeneration
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• at 8 to 10 months, ramified spine density is decreased 33% compared to in wild-type mice
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• at 8 to 10 months
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• at 13 to 14 months
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• at 8 to 10 months and at 13 to 14 months
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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