All Phenotypes Kcnh2<tm1Hjd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnh2^tm1Hjd
targeted mutation 1, Henry J Duff
MGI:2652959

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnh2^tm1Hjd/Kcnh2^tm1Hjd	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:2652979

Allelic Composition	Kcnh2^tm1Hjd/Kcnh2^tm1Hjd
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnh2^tm1Hjd mutation (0 available); any Kcnh2 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased heart rate ( J:82249 )

• spontaneous and abrupt bradycardias in 6 of 21 mice examined although average cycle lengths and intervals were similar to controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
short QT syndrome		DOID:0050793	OMIM:609620 OMIM:609621 OMIM:609622	J:82249

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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