Phenotypes associated with this allele

• Allele Symbol: Mvp^tm1Wie
• Allele Name: targeted mutation 1, Erik A C Wiemer
• Allele ID: MGI:2447742
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mvp^tm1Wie/Mvp^tm1Wie	involves: 129P2/OlaHsd * C57BL/6	MGI:2653536

Genotype
MGI:2653536

hm1

• Allelic Composition: Mvp^tm1Wie/Mvp^tm1Wie
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:80831 , J:113597 )

• No physical abnormalities were seen up to an age of 16 months (J:80831)

• Mice were histologically normal (J:80831)

• resistance to cytostatic agents was essentially normal (J:80831)

• macrophage migration and function are normal (J:113597)

• analysis of dendritic cell function indicates that antigen handling and presentation, and in vivo immune functions like induction of oral tolerance and T cell-mediated humoral responses, are similar to wild-type (J:113597)