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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Idd3C57BL/6
C57BL/6
MGI:2389019
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Idd3C57BL/6/Idd3C57BL/6 involves: C57BL/6 * NOD MGI:2674232
hm2
 		Idd3C57BL/6/Idd3C57BL/6 NOD.B6-Idd3C57BL/6 MGI:3623819
cx3
 		Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ 		involves: C57BL/6 * C57BL/10SnJ * NOD MGI:2674234
cx4
 		Idd10C57BL/6J/Idd10C57BL/6J
Idd3C57BL/6/Idd3C57BL/6 		involves: C57BL/6 * NOD MGI:3038854
cx5
 		Airetm1.1Doi/Airetm1.1Doi
Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ 		NOD.Cg-Idd3C57BL/6 Idd5C57BL/10SnJ Airetm1.1Doi/Doi MGI:3793705


Genotype
MGI:2674232
hm1
Allelic
Composition		 Idd3C57BL/6/Idd3C57BL/6
Genetic
Background		 involves: C57BL/6 * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:52572 )
• resistance to insulin dependent diabetes




Genotype
MGI:3623819
hm2
Allelic
Composition		 Idd3C57BL/6/Idd3C57BL/6
Genetic
Background		 NOD.B6-Idd3C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:108210 )
• resistance to insulin-dependent diabetes

immune system
decreased susceptibility to autoimmune diabetes ( J:120349 )
• resistance to type 1 diabetes




Genotype
MGI:2674234
cx3
Allelic
Composition		 Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ
Genetic
Background		 involves: C57BL/6 * C57BL/10SnJ * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
Idd5C57BL/10SnJ mutation (5 available); any Idd5 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:71276 )
• partial reversal of autoimmune exocrinopathy markers




Genotype
MGI:3038854
cx4
Allelic
Composition		 Idd10C57BL/6J/Idd10C57BL/6J
Idd3C57BL/6/Idd3C57BL/6
Genetic
Background		 involves: C57BL/6 * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd10C57BL/6J mutation (7 available); any Idd10 mutation (10 available)
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:42103 )
• resistance to type 1 diabetes




Genotype
MGI:3793705
cx5
Allelic
Composition		 Airetm1.1Doi/Airetm1.1Doi
Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ
Genetic
Background		 NOD.Cg-Idd3C57BL/6 Idd5C57BL/10SnJ Airetm1.1Doi/Doi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Airetm1.1Doi mutation (2 available); any Aire mutation (52 available)
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
Idd5C57BL/10SnJ mutation (5 available); any Idd5 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

digestive/alimentary system

endocrine/exocrine glands
abnormal pancreas physiology ( J:107432 )
• Background Sensitivity: the pancreatitis associated with the Airetm1.1Doi allele on the NOD background is much less severe when these alleles of Idd3 and Idd5 are present
• Background Sensitivity: the gastritis associated with the Airetm1.1Doi allele on the NOD background is much less severe when these alleles of Idd3 and Idd5 are present




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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory