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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dstncorn1-2J
corneal disease 1, 2 Jackson
MGI:2388156
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dstncorn1-2J/Dstncorn1-2J C57BL/6JSmn-Dstncorn1-2J/J MGI:2660805
ht2
Dstncorn1/Dstncorn1-2J involves: A/WySn * brachy stock * C57BL/6JSmn MGI:3817224


Genotype
MGI:2660805
hm1
Allelic
Composition
Dstncorn1-2J/Dstncorn1-2J
Genetic
Background
C57BL/6JSmn-Dstncorn1-2J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dstncorn1-2J mutation (1 available); any Dstn mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• unlike Dstncorn1 homozygotes corneal vascularization is not seen (J:83125)
• unlike Dstncorn1 homozygotes neutrophil and macrophage infiltration of the cornea is not seen (J:139239)
• epithelial lesion characterized by focal epithelial thickening and enlarged surface
• epithelial cells with degenerating nuclei
• phenotype is milder than in Dstncorn1 homozygotes




Genotype
MGI:3817224
ht2
Allelic
Composition
Dstncorn1/Dstncorn1-2J
Genetic
Background
involves: A/WySn * brachy stock * C57BL/6JSmn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dstncorn1 mutation (1 available); any Dstn mutation (42 available)
Dstncorn1-2J mutation (1 available); any Dstn mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• unlike Dstncorn1 homozygotes corneal vascularization is not seen
• epithelial proliferation





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory