Phenotypes associated with this allele

• Allele Symbol: Incenp^tm1Khac
• Allele Name: targeted mutation 1, K H Andy Choo
• Allele ID: MGI:2386970
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Incenp^tm1Khac/Incenp^tm1Khac	involves: 129P2/OlaHsd * C57BL/6	MGI:2669827

Genotype
MGI:2669827

hm1

• Allelic Composition: Incenp^tm1Khac/Incenp^tm1Khac
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:56343 )

• homozygous embryos died prior to E8.5

embryo

abnormal embryonic tissue morphology ( J:56343 )

• embryonic cells are large, disorganized and show distinct abnormalities including nuclei of abnormal size and mitotic abnormalities

absent blastocoele ( J:56343 )

• cells of the embryo fail to organize into embryonic and extraembryonic layers

absent inner cell mass ( J:56343 )

• absent ICM; cells fail to organize into ICM

abnormal extraembryonic tissue morphology ( J:56343 )