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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fechtm1Dab
targeted mutation 1, David A Brenner
MGI:2384729
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fechtm1Dab/Fechtm1Dab involves: 129P2/OlaHsd * C57BL/6 MGI:2664559
ht2
 		Fechtm1Dab/Fech+ involves: 129P2/OlaHsd * C57BL/6 MGI:2664560


Genotype
MGI:2664559
hm1
Allelic
Composition		 Fechtm1Dab/Fechtm1Dab
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fechtm1Dab mutation (0 available); any Fech mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:78345 )
• embryos are viable until at least E3.5 but die sometime before E9




Genotype
MGI:2664560
ht2
Allelic
Composition		 Fechtm1Dab/Fech+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fechtm1Dab mutation (0 available); any Fech mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
erythropoietic protoporphyria DOID:13270 OMIM:177000
OMIM:300752
 J:78345




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory