Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1.1Mro mutation
(0 available);
any
Pten mutation
(81 available)
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mortality/aging
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• authors state that mice exhibit a phenotype that mimicked the phenotype observed in other Pten knockout mice
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embryo
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• authors state that mice exhibit a phenotype that mimicked the phenotype observed in other Pten knockout mice
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neoplasm
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• authors state that mice exhibit a phenotype that mimicked the phenotype observed in other Pten knockout mice
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Allelic Composition |
Ptentm1.1Mro/Pten+
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Genetic Background |
Not Specified |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1.1Mro mutation
(0 available);
any
Pten mutation
(81 available)
|
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endocrine/exocrine glands
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• at 10 months of age, 73% of mice develop a pheochromocytoma
• tumors do not show accumulation of succinate
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neoplasm
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• at 10 months of age, 73% of mice develop a pheochromocytoma
• tumors do not show accumulation of succinate
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• lung micro-metastasis are seen in 64% of mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1.1Mro mutation
(0 available);
any
Pten mutation
(81 available)
Sdhbtm1.2Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
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endocrine/exocrine glands
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• at 10 months of age, 80% of mice develop a pheochromocytoma
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neoplasm
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• at 10 months of age, 80% of mice develop a pheochromocytoma
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• lung micro-metastasis are seen in 73% of mice
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