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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ucp3tm1Brnd
targeted mutation 1, Martin D Brand
MGI:2183204
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ucp3tm1Brnd/Ucp3tm1Brnd B6.Cg-Ucp3tm1Brnd MGI:3852052
hm2
Ucp3tm1Brnd/Ucp3tm1Brnd Not Specified MGI:3852053


Genotype
MGI:3852052
hm1
Allelic
Composition
Ucp3tm1Brnd/Ucp3tm1Brnd
Genetic
Background
B6.Cg-Ucp3tm1Brnd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3tm1Brnd mutation (0 available); any Ucp3 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• skeletal muscle mitochondria proton conductance is insensitive to superoxide treatment unlike wild-type mitochondria




Genotype
MGI:3852053
hm2
Allelic
Composition
Ucp3tm1Brnd/Ucp3tm1Brnd
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3tm1Brnd mutation (0 available); any Ucp3 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• when fed a high-fat diet, intramuscular triglyceride levels are lower than in similarly treated wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory