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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ncam1tm1Mag
targeted mutation 1, Terry Magnuson
MGI:2182406
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ncam1tm1Mag/Ncam1tm1Mag involves: 129S2/SvPas * CF-1 MGI:2182569


Genotype
MGI:2182569
hm1
Allelic
Composition
Ncam1tm1Mag/Ncam1tm1Mag
Genetic
Background
involves: 129S2/SvPas * CF-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncam1tm1Mag mutation (0 available); any Ncam1 mutation (65 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• the circadian period in DD conditions is significantly shorter in mutants, 23.50 hours compared to 23.90 hours in wild-type littermates
• the duration of the active period increased under DD conditions so that after 3 weeks rhythmicity is lost

vision/eye
• appearance of cell bodies in the plexiform layers

nervous system
• abnormal pyramidal layer; dispersed and often split
• reduced granule cell number, disorganized granule cell layer and abnormal migration of granule cell precursors
• approximately half the size of heterozygous littermates
• reduced length of lobule IV





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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory