behavior/neurological

decreased grip strength ( J:77600 )

• weakened grip strength in one hindlimb first observed by 12-14 months and spreading rapidly to other limbs

paralysis ( J:77600 )

• complete paralysis occurs two weeks after onset of weakened grip strength

hindlimb paralysis ( J:77600 )

• hindlimb paralysis is first observed at 12-14 months

muscle

muscular atrophy ( J:77600 )

progressive muscle weakness ( J:77600 )

Mouse Models of Human Disease		OMIM ID	Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1		105400	J:77600