Analysis Tools
mortality/aging
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• number of viable embryos less than expected at E3.5
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• no viable embryos present at E8.5
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Allele Symbol Allele Name Allele ID |
Pik3cbtm1Nbm targeted mutation 1, Robert L Nussbaum MGI:2180703 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Phase contrast microscopy of blastobysts flushed at day 3.5 d.p.c.
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• number of viable embryos less than expected at E3.5
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• no viable embryos present at E8.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mild hyperinsulinemia in the fasted state at 6 months of age
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• mild glucose intolerance in glucose tolerance test at 6 months of age but not at early ages
• however, no differences seen in glucose clearance during an insulin tolerance test
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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