Mouse Genome Informatics
tg1
    Tg(Ckmm-Cav3)1Ysu/0
involves: C57BL/Slc * DBA/Slc
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
muscle
• at 6 weeks of age
• skeletal muscles exhibit increased neuronal nitric oxide synthase (nNOS) activity compared to in wild-type muscles
• at 6 weeks of age, mice exhibit myopathic features, including variation in fiber size, atrophic fibers, internally placed nuclei, and increased endomysium compared with wild-type mice

growth/size/body
• at 6 weeks of age

skeleton
• at 6 weeks of age

behavior/neurological
• at 6 weeks of age

homeostasis/metabolism
• skeletal muscles exhibit increased neuronal nitric oxide synthase (nNOS) activity compared to in wild-type muscles

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Limb-Girdle, Type 1C; LGMD1C 607801 J:67174