Mouse Genome Informatics
hm1
    Acadvltm1Uab/Acadvltm1Uab
involves: 129S6/SvEvTac * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
homeostasis/metabolism
• C16 and C18 acylcarnitines are elevated in bile, blood, and serum of fasted mutants
• mild lipid accumulation in the heart is seen in fasted mutants
• mild reduction in mitochondrial acyl-CoA dehydrogenase activity toward palmitoyl-CoA and oleoyl-CA in the liver

liver/biliary system
• fasted mice display mild steatosis, with droplets of varying sizes in many hepatocytes

cardiovascular system
• fasted mice display a mild, diffuse fatty change in hearts


Mouse Genome Informatics
cx2
    Acadltm1Uab/Acadltm1Uab
Acadvltm1Uab/Acadvltm1Uab

involves: 129S6/SvEvTac * C57BL/6NTac
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
• partially cannibalized pups are observed, indicating loss occurs as late as the periparturient period