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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Scnn1btm1Wsh
targeted mutation 1, Michael J Welsh
MGI:2179819
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Scnn1btm1Wsh/Scnn1btm1Wsh involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:2181800


Genotype
MGI:2181800
hm1
Allelic
Composition
Scnn1btm1Wsh/Scnn1btm1Wsh
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scnn1btm1Wsh mutation (1 available); any Scnn1b mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• die within 2 days after birth

homeostasis/metabolism
• lower potassium concentration and higher sodium concentration in the urine, but the chloride concentration is normal

growth/size/body

renal/urinary system
• lower potassium concentration and higher sodium concentration in the urine, but the chloride concentration is normal

respiratory system
N
• do not exhibit respiratory failure or abnormal breathing and have normal lungs

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autosomal recessive pseudohypoaldosteronism type 1 DOID:0060854 OMIM:264350
J:53058





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory