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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
MitfRorp
retinal orange patches
MGI:2178357
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
MitfRorp/MitfRorp involves: BALB/cAnN * C3H/HeN MGI:2686997
ht2
MitfRorp/Mitf+ involves: BALB/cAnN * C3H/HeN MGI:2686998
ht3
MitfMi-H/MitfRorp involves: BALB/cAnN * C3H/HeN MGI:2686996


Genotype
MGI:2686997
hm1
Allelic
Composition
MitfRorp/MitfRorp
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfRorp mutation (2 available); any Mitf mutation (56 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• abnormal pigmentation of the irises

vision/eye
• abnormal pigmentation of the irises
• an increased frequency of coloboma was noted
• reduced total pigment with remaining pigment in scattered patches

integument




Genotype
MGI:2686998
ht2
Allelic
Composition
MitfRorp/Mitf+
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfRorp mutation (2 available); any Mitf mutation (56 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice were described as having a slightly paler ears
• mice were described as having a slightly paler coat than wild-type
• mice were described as having a slightly paler tails

hearing/vestibular/ear
• mice were described as having a slightly paler ears

limbs/digits/tail
• mice were described as having a slightly paler tails

vision/eye
• patches of orange were noted on the retina

craniofacial
• mice were described as having a slightly paler ears

integument
• mice were described as having a slightly paler ears
• mice were described as having a slightly paler coat than wild-type
• mice were described as having a slightly paler tails

growth/size/body
• mice were described as having a slightly paler ears




Genotype
MGI:2686996
ht3
Allelic
Composition
MitfMi-H/MitfRorp
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-H mutation (1 available); any Mitf mutation (56 available)
MitfRorp mutation (2 available); any Mitf mutation (56 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice are described as white
• mild iris transillumination; brown pigmentation of the irises

vision/eye
• mild iris transillumination; brown pigmentation of the irises
• an increased frequency of coloboma was noted
• described as depigmented

integument
• mice are described as white





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory