Mouse Genome Informatics
hm1
    MitfRorp/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• abnormal pigmentation of the irises

vision/eye
• abnormal pigmentation of the irises
• an increased frequency of coloboma was noted
• reduced total pigment with remaining pigment in scattered patches

integument


Mouse Genome Informatics
ht2
    MitfRorp/Mitf+
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• mice were described as having a slightly paler ears
• mice were described as having a slightly paler coat than wild-type
• mice were described as having a slightly paler tails

hearing/vestibular/ear
• mice were described as having a slightly paler ears

limbs/digits/tail
• mice were described as having a slightly paler tails

vision/eye
• patches of orange were noted on the retina

craniofacial
• mice were described as having a slightly paler ears

integument
• mice were described as having a slightly paler ears
• mice were described as having a slightly paler coat than wild-type
• mice were described as having a slightly paler tails


Mouse Genome Informatics
ht3
    MitfMi-H/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• mice are described as white
• mild iris transillumination; brown pigmentation of the irises

vision/eye
• mild iris transillumination; brown pigmentation of the irises
• an increased frequency of coloboma was noted
• described as depigmented

integument
• mice are described as white