Mouse Genome Informatics
hm1
     MitfRorp/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
abnormal iris pigmentation ( J:75964 )
• abnormal pigmentation of the irises

vision/eye
abnormal iris pigmentation ( J:75964 )
• abnormal pigmentation of the irises
coloboma ( J:75964 )
• an increased frequency of coloboma was noted
abnormal retina morphology ( J:75964 )
• reduced total pigment with remaining pigment in scattered patches

integument


Mouse Genome Informatics
ht2
     MitfRorp/Mitf+
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
decreased ear pigmentation ( J:75964 )
• mice were described as having a slightly paler ears
diluted coat color ( J:75964 )
• mice were described as having a slightly paler coat than wild-type
decreased tail pigmentation ( J:75964 )
• mice were described as having a slightly paler tails

hearing/vestibular/ear
decreased ear pigmentation ( J:75964 )
• mice were described as having a slightly paler ears

limbs/digits/tail
decreased tail pigmentation ( J:75964 )
• mice were described as having a slightly paler tails

vision/eye
abnormal retina morphology ( J:75964 )
• patches of orange were noted on the retina

craniofacial
decreased ear pigmentation ( J:75964 )
• mice were described as having a slightly paler ears

integument
decreased ear pigmentation ( J:75964 )
• mice were described as having a slightly paler ears
diluted coat color ( J:75964 )
• mice were described as having a slightly paler coat than wild-type
decreased tail pigmentation ( J:75964 )
• mice were described as having a slightly paler tails


Mouse Genome Informatics
ht3
     MitfMi-H/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
absent coat pigmentation ( J:75964 )
• mice are described as white
abnormal iris pigmentation ( J:75964 )
• mild iris transillumination; brown pigmentation of the irises

vision/eye
abnormal iris pigmentation ( J:75964 )
• mild iris transillumination; brown pigmentation of the irises
coloboma ( J:75964 )
• an increased frequency of coloboma was noted
abnormal ocular fundus morphology ( J:75964 )
• described as depigmented

integument
absent coat pigmentation ( J:75964 )
• mice are described as white