Mouse Genome Informatics
hm1
    MitfMi-H/MitfMi-H
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• mice were described as unpigmented
• mice were described as completely unpigmented

vision/eye
• absent eyes; a small amount of tissue was present in the orbit but nothing resembling eye tissue

integument
• mice were described as unpigmented
• mice were described as completely unpigmented


Mouse Genome Informatics
ht2
    MitfMi-H/Mitf+
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• mice were described as having pale ears
• described as having pale patches on their coats, most often as a head or belly spot
• mice were described as having pale feet
• mice were described as having pale tails

hearing/vestibular/ear
• mice were described as having pale ears

limbs/digits/tail
• mice were described as having pale tails

vision/eye
• eye examination showed mild iris transillumination

craniofacial
• mice were described as having pale ears

integument
• mice were described as having pale ears
• described as having pale patches on their coats, most often as a head or belly spot
• mice were described as having pale feet
• mice were described as having pale tails

growth/size/body
• mice were described as having pale ears


Mouse Genome Informatics
ht3
    MitfMi-H/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
pigmentation
• mice are described as white
• mild iris transillumination; brown pigmentation of the irises

vision/eye
• mild iris transillumination; brown pigmentation of the irises
• an increased frequency of coloboma was noted
• described as depigmented

integument
• mice are described as white