Mouse Genome Informatics
hm1
     MitfMi-H/MitfMi-H
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
absent coat pigmentation ( J:75964 )
• mice were described as unpigmented
abnormal skin pigmentation ( J:75964 )
• mice were described as completely unpigmented

vision/eye
anophthalmia ( J:75964 )
• absent eyes; a small amount of tissue was present in the orbit but nothing resembling eye tissue

integument
absent coat pigmentation ( J:75964 )
• mice were described as unpigmented
abnormal skin pigmentation ( J:75964 )
• mice were described as completely unpigmented


Mouse Genome Informatics
ht2
     MitfMi-H/Mitf+
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
decreased ear pigmentation ( J:75964 )
• mice were described as having pale ears
irregular coat pigmentation ( J:75964 )
• described as having pale patches on their coats, most often as a head or belly spot
abnormal foot pigmentation ( J:75964 )
• mice were described as having pale feet
decreased tail pigmentation ( J:75964 )
• mice were described as having pale tails

hearing/vestibular/ear
decreased ear pigmentation ( J:75964 )
• mice were described as having pale ears

limbs/digits/tail
decreased tail pigmentation ( J:75964 )
• mice were described as having pale tails

vision/eye
abnormal iris morphology ( J:75964 )
• eye examination showed mild iris transillumination

craniofacial
decreased ear pigmentation ( J:75964 )
• mice were described as having pale ears

integument
decreased ear pigmentation ( J:75964 )
• mice were described as having pale ears
irregular coat pigmentation ( J:75964 )
• described as having pale patches on their coats, most often as a head or belly spot
abnormal foot pigmentation ( J:75964 )
• mice were described as having pale feet
decreased tail pigmentation ( J:75964 )
• mice were described as having pale tails


Mouse Genome Informatics
ht3
     MitfMi-H/MitfRorp
involves: BALB/cAnN * C3H/HeN
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
pigmentation
absent coat pigmentation ( J:75964 )
• mice are described as white
abnormal iris pigmentation ( J:75964 )
• mild iris transillumination; brown pigmentation of the irises

vision/eye
abnormal iris pigmentation ( J:75964 )
• mild iris transillumination; brown pigmentation of the irises
coloboma ( J:75964 )
• an increased frequency of coloboma was noted
abnormal ocular fundus morphology ( J:75964 )
• described as depigmented

integument
absent coat pigmentation ( J:75964 )
• mice are described as white