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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
MitfMi-H
microphthalmia Harwell
MGI:2178353
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
MitfMi-H/MitfMi-H involves: BALB/cAnN * C3H/HeN MGI:2686994
ht2
MitfMi-H/Mitf+ involves: BALB/cAnN * C3H/HeN MGI:2686995
ht3
MitfMi-H/MitfRorp involves: BALB/cAnN * C3H/HeN MGI:2686996


Genotype
MGI:2686994
hm1
Allelic
Composition
MitfMi-H/MitfMi-H
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-H mutation (1 available); any Mitf mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice were described as unpigmented
• mice were described as completely unpigmented

vision/eye
• absent eyes; a small amount of tissue was present in the orbit but nothing resembling eye tissue

integument
• mice were described as unpigmented
• mice were described as completely unpigmented




Genotype
MGI:2686995
ht2
Allelic
Composition
MitfMi-H/Mitf+
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-H mutation (1 available); any Mitf mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice were described as having pale ears
• described as having pale patches on their coats, most often as a head or belly spot
• mice were described as having pale feet
• mice were described as having pale tails

hearing/vestibular/ear
• mice were described as having pale ears

limbs/digits/tail
• mice were described as having pale tails

vision/eye
• eye examination showed mild iris transillumination

craniofacial
• mice were described as having pale ears

integument
• mice were described as having pale ears
• described as having pale patches on their coats, most often as a head or belly spot
• mice were described as having pale feet
• mice were described as having pale tails

growth/size/body
• mice were described as having pale ears




Genotype
MGI:2686996
ht3
Allelic
Composition
MitfMi-H/MitfRorp
Genetic
Background
involves: BALB/cAnN * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-H mutation (1 available); any Mitf mutation (57 available)
MitfRorp mutation (2 available); any Mitf mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice are described as white
• mild iris transillumination; brown pigmentation of the irises

vision/eye
• mild iris transillumination; brown pigmentation of the irises
• an increased frequency of coloboma was noted
• described as depigmented

integument
• mice are described as white





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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory