Mouse Genome Informatics
hm1
     Apobtm4Sgy/Apobtm4Sgy
involves: 129S4/SvJae * C57BL/6
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
mortality/aging
complete prenatal lethality ( J:46549 )
• majority die in utero, with small percentage stillborn or dead perinatally

cardiovascular system
hemorrhage ( J:46549 )
• from brain into amniotic fluid

embryogenesis

growth/size

liver/biliary system
herniated liver ( J:46549 )
• liver herniation into the umbilical cord

nervous system


Mouse Genome Informatics
ht2
     Apobtm2Sgy/Apobtm4Sgy
involves: 129/Sv * 129S4/SvJae * C57BL/6
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
homeostasis/metabolism

Mouse Models of Human Disease
 OMIM IDRef(s)
Apolipoprotein B; APOB 107730 J:46549