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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Apobtm4Sgy
targeted mutation 4, Stephen G Young
MGI:2157775
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Apobtm4Sgy/Apobtm4Sgy involves: 129S4/SvJae * C57BL/6 MGI:2662513
ht2
Apobtm2Sgy/Apobtm4Sgy involves: 129/Sv * 129S4/SvJae * C57BL/6 MGI:2672089


Genotype
MGI:2662513
hm1
Allelic
Composition
Apobtm4Sgy/Apobtm4Sgy
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apobtm4Sgy mutation (0 available); any Apob mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• majority die in utero, with small percentage stillborn or dead perinatally (J:46549)
• majority die in utero, with small percentage stillborn or dead perinatally (J:46549)

cardiovascular system
• from brain into amniotic fluid (J:46549)
• from brain into amniotic fluid (J:46549)

embryogenesis

growth/size/body

liver/biliary system
• liver herniation into the umbilical cord (J:46549)
• liver herniation into the umbilical cord (J:46549)

nervous system




Genotype
MGI:2672089
ht2
Allelic
Composition
Apobtm2Sgy/Apobtm4Sgy
Genetic
Background
involves: 129/Sv * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apobtm2Sgy mutation (4 available); any Apob mutation (14 available)
Apobtm4Sgy mutation (0 available); any Apob mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• observed in females (J:46549)
• observed in females (J:46549)

Mouse Models of Human Disease
OMIM ID Ref(s)
Apolipoprotein B; APOB 107730 J:46549





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory