Mouse Genome Informatics
hm1
     Apobtm5Sgy/Apobtm5Sgy
involves: 129S4/SvJae * C57BL/6
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
mortality/aging
postnatal lethality ( J:51549 )
• 50% do not survive until weaning

homeostasis/metabolism
decreased circulating LDL cholesterol level ( J:51549 )
• on high fat diet, low plasma LDL is observed
decreased circulating VLDL cholesterol level ( J:51549 )
• on high fat diet, low plasma VLDL is observed; VLDL particles are small

Mouse Models of Human Disease
 OMIM IDRef(s)
Apolipoprotein B; APOB 107730 J:51549