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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pax64Neu
4, Neuherberg
MGI:2156741
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pax64Neu/Pax64Neu either: (involves: 102 * C3H) or (involves: C3H) MGI:2173411
hm2
Pax64Neu/Pax64Neu involves: C3HeB/FeJ MGI:3521823
ht3
Pax64Neu/Pax6+ either: (involves: 102 * C3H) or (involves: C3H) MGI:3590308


Genotype
MGI:2173411
hm1
Allelic
Composition
Pax64Neu/Pax64Neu
Genetic
Background
either: (involves: 102 * C3H) or (involves: C3H)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax64Neu mutation (1 available); any Pax6 mutation (58 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• survive 24-36 hours after birth

vision/eye
• occasionally with a distinct optic pit and underlying pigmentation

craniofacial
• hyperplasia of cartilaginous parts of nasal anlage and reduced nasal cavities
• reduced lateral nasal processes
• reduced medial nasal processes




Genotype
MGI:3521823
hm2
Allelic
Composition
Pax64Neu/Pax64Neu
Genetic
Background
involves: C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax64Neu mutation (1 available); any Pax6 mutation (58 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• some alteration of the dorso-ventral telencephalic boundary, however no decrease in the number of neurons in the cerebral cortex or increase in the subventricular zone precursors, indicating that the homeodomain is not required for neurogenesis in the cortex




Genotype
MGI:3590308
ht3
Allelic
Composition
Pax64Neu/Pax6+
Genetic
Background
either: (involves: 102 * C3H) or (involves: C3H)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax64Neu mutation (1 available); any Pax6 mutation (58 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• abnormalities
• anterior polar opacity very moderate
• but very slight (J:73625)





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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory