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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Myo7a816SB
shaker 816SB
MGI:2155423
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Myo7a816SB/Myo7a816SB involves: BALB/cRl MGI:3587760
hm2
Myo7a816SB/Myo7a816SB involves: BALB/cRl * 47BS/Rl MGI:3587763


Genotype
MGI:3587760
hm1
Allelic
Composition
Myo7a816SB/Myo7a816SB
Genetic
Background
involves: BALB/cRl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo7a816SB mutation (2 available); any Myo7a mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
• abnormal hair cell development
• no cochlear electrophysiology responses

nervous system
• abnormal hair cell development

Mouse Models of Human Disease
OMIM ID Ref(s)
Usher Syndrome, Type I; USH1 276900 J:42644




Genotype
MGI:3587763
hm2
Allelic
Composition
Myo7a816SB/Myo7a816SB
Genetic
Background
involves: BALB/cRl * 47BS/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo7a816SB mutation (2 available); any Myo7a mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
• disorganized formation of stereocilia rows
• some hair cells with several small clumps of stereocilia
• orientation of rows of cochlear hair cell stereocilia erratic
• no cochlear microphonics responses
• no summating potential responses

nervous system
• disorganized formation of stereocilia rows
• some hair cells with several small clumps of stereocilia
• orientation of rows of cochlear hair cell stereocilia erratic
• no cochlear microphonics responses

Mouse Models of Human Disease
OMIM ID Ref(s)
Usher Syndrome, Type I; USH1 276900 J:46373





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory