Mouse Genome Informatics
hm1
    Npr2cn-2J/Npr2cn-2J
B6;CBACa Aw-J/A-Npr2cn-2J/GrsrJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype

Npr2cn-2J/Npr2cn-2J mice have domed heads and shortened long bones and tail compared to controls

reproductive system
• while oocytes in late antral follicles are usually maintained at the germinal vesicle stage with arrested meiosis, 80% of those in homozygotes have already resumed meiosis (J:164870)


Mouse Genome Informatics
hm2
    Npr2cn-2J/Npr2cn-2J
B6;CBACa-Aw-J/A-Kcnj6wv/+
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
craniofacial
• round head

limbs/digits/tail
• short, thick femurs

skeleton
N
• relatively normal vertebrae (J:72465)
• short, thick femurs
• disorganized growth plates
• one animal exhibited splayed ribs

growth/size/body
• round head

Mouse Models of Human Disease
OMIM IDRef(s)
Achondroplasia; ACH 100800 J:72465