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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hoxb1tm1Brd
targeted mutation 1, Allan Bradley
MGI:2151762
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hoxb1tm1Brd/Hoxb1tm1Brd involves: 129S7/SvEvBrd * C57BL/6 MGI:2675275


Genotype
MGI:2675275
hm1
Allelic
Composition
Hoxb1tm1Brd/Hoxb1tm1Brd
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxb1tm1Brd mutation (0 available); any Hoxb1 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 98% of mice die at birth

nervous system
• at E10.5 to E11.5, the facial branchiomotor neurons and contralateral vestibularacoustic efferent neurons are incorrectly specified
• visceromotor neurons exhibit abnormal axonal trajectories
• the identity of r4 is properly established but not properly maintained as determined by marker expression
• at E10.5 to E11.5, the facial branchiomotor neurons and contralateral vestibularacoustic efferent neurons are absent
• visceromotor neurons exhibit abnormal axonal trajectories

embryo
• the identity of r4 is properly established but not properly maintained as determined by marker expression

cellular
• at E10.5 to E11.5, the facial branchiomotor neurons and contralateral vestibularacoustic efferent neurons are incorrectly specified
• visceromotor neurons exhibit abnormal axonal trajectories





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory