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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mapttm1Noh
targeted mutation 1, Nobutaka Hirokawa
MGI:2138030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mapttm1Noh/Mapttm1Noh involves: 129S4/SvJae MGI:2174969


Genotype
MGI:2174969
hm1
Allelic
Composition
Mapttm1Noh/Mapttm1Noh
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm1Noh mutation (0 available); any Mapt mutation (401 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• abnormal cerebellar parallel fiber axons; reduction in microtubule (MT) number and density and reduction in frequency of cross-bridges between MTs
• mice exhibit no other obvious abnormalities

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Alzheimer Disease; AD 104300 J:19030





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory